I have never been to France ,therefore I can't advise you.这句话对么?therefore可以这样用吗?如果把therefore换成and therefore对吗?如果and therefore前没有逗号(像这样I have never been to France and therefore I can't advise you

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I have never been to France ,therefore I can't advise you.这句话对么?
therefore可以这样用吗?如果把therefore换成and therefore对吗?
如果and therefore前没有逗号(像这样I have never been to France and therefore I can't advise you.

应该是:“,therefore,”

可以的,and 和therefore都是连词,用一个就可以了

无所谓

不可以说and therefore
只能这样用,therefore本身就连接两个句子了。

ad.
1. 因此,所以
He was down with the flu, and therefore couldn't come to the party.
他患了流行性感冒,因此未能前来参加宴会。
adv.
1. 因此, 所以
He was ill, and therefore could not come.
他病了, 所以未能来。

therefore本身即为连词,连接两个独立句子,不必再加and.
逗号的存在与否应不重要,以下两种形式均可:
1.I have never been to France ,therefore I can't advise you.
2.I have never been to France therefore I can't advise you.